CJCU

Chem. J. Chinese Universities ›› 2013, Vol. 34 ›› Issue (6): 1347.doi: 10.7503/cjcu20120976

• Analytical Chemistry • Previous Articles     Next Articles

Preparation and Application of Barium Fluoride Particles as Stationary Phase for TLC-FTIR Analysis

LIU Wei1,2, WU Hai-Jun2,3, WANG Xiu-Peng4, ZHU Qing5, KANG Ting-Guo1, HE An-Qi2, WENG Shi-Fu2, YANG Zhan-Lan2, XIA Jin-Ming6, XU Yi-Zhuang2, WU Jin-Guang2   

  1. 1. College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China;
    2. State Key Laboratory of Rare Earth Materials Chemistry and Application, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China;
    3. Mongolia Medical College, Inner Mongolia University for the Nationalities, Tongliao 028000, China;
    4. Linyi Institute of Technical Supervision Information, Linyi 276004, China;
    5. Engineering Technology Institute, College of Engineering, Peking University, Beijing 100871, China;
    6. Shenyang Dootel Biopharmaceutical Research Center, Shenyang 110031, China
  • Received:2012-10-30 Online:2013-06-10 Published:2013-05-17

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Abstract:

In this study, we modified the preparation of barium fluoride fine particles by a reaction between sodium fluoride and barium chloride. However, the experimental result turned out that the yield of BaF2 is rather low. By inductive coupled plasma(ICP) and X-ray diffraction(XRD) analysis, we found barium fluorochloride was produced with barium fluoride in the reaction. During the washing of precipitates, barium fluorochloride was dissolved in water with low concentration of Cl- and F-, leading to the lost of barium ions and low yield of BaF2. To solve the problem, aqueous solution of NaF was used to wash the product of the reaction between barium chloride and sodium fluoride. Both XRD and ICP results confirmed that barium fluorochloride converted into barium fluoride. Hence, the yield of barium fluoride increases significantly. The average diameter of the BaF2 particles is around 100 nm by SEM and nanometer particle size analyzer. We used settlement volatilization method to prepare TLC plate without using polymeric adhesive. TLC experiments prove that the TLC plate using BaF2 fine particles as stationary phase can separate the mixture of Rhodamine B and Malachite green. FTIR analysis confirms that the FTIR spectra of the separated Rhodamine B and Malachite green spots are in good agreement with the FTIR spectra of pure Rhodamine B and Malachite green.

Key words: Barium fluoride, Stationary phase, Thin-layer chromatography, Infrared spectroscopy, Hyphenating technique

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