Chem. J. Chinese Universities ›› 1998, Vol. 19 ›› Issue (12): 1946.

• Articles • Previous Articles     Next Articles

Studies on Bio-rational Design of Photosystem Ⅱ Inhibitors(Ⅴ)——Synthesis and Hill Inhibitory Activities of Ethyl Arylamideacrylates and Pyrimidone

LIU Hua-Yin1, YANG Guang-Fu1, TAN Hui-Fen1, YANG Hua-Zheng1, LAI Lu-Hua2   

  1. 1. National Key Laboratory of Elemen to-organic Chemistry, Institute of Elemen to-organic Chemistry, Nankai University, Tianjin, 300071;
    2. Phys. Chem. Institute of Peking, Beijing, 100871
  • Received:1998-01-14 Online:1998-12-24 Published:1998-12-24

Abstract: Based on target's structure and using bio rational molecular design, the title compounds have been designed and synthesized. The structure of pyrimidone 3a was confirmed by X-ray. Their Hill inhibitory activities were tested, and it was found that some of them showed good inhibition.

Key words: Substituted acrylates, Pyrimidonyl, X-ray, Hill inhibitory

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