Studies on Simulation Chemistry of Cu-Zn Superoxide Dismutase

Abstract

Abstract: This paper describes comprehensively the significance and current situation ofsimulation chemistry for Cu-Zn superoxide dismutase (SOD) and the author'Sachievementsin this area.Are discussed the simulation for the active center of SOD, the behavior of theimidazolate bridge by the model complexes, the relationship between structures and func-tions of copper(Ⅱ) center, the kinetics for disproportionating superoxide ion by the SODmodel compounds and biological functions.Based on the comparison of structures and func-tions between SODand its model compounds, the structural features of the excellent SODmodel compounds are also presented.

Key words: Cu-Zn superoxide dismutase, Simulat, Structure, Kinetics, Biological functionion

CLC Number:

O641.4
Q554

TrendMD:

LUO Qin-Hui. Studies on Simulation Chemistry of Cu-Zn Superoxide Dismutase[J]. Chem. J. Chinese Universities, 1997, 18(7): 1012.

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Studies on Simulation Chemistry of Cu-Zn Superoxide Dismutase

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