The Research on Development of Novel Pesticides (Ⅲ)--The Synthesis of Imidazolinones

Abstract

Abstract: 3-(3,5-dichlorophenyl)-1-isopropyl-carbamoylhydantoin has been developed as a commercial fungicide known as R'oyral. Nevertheless, the starting material 3,5-dichloroaniline for the synthesis is not easily available. The latter was replaced by other substituted anilines here, followed by conversion to isocyanates by triphosgene and cyclization into heterocycles in one-pot reaction. 22 new compounds were synthesized with all structures confirmed by elementary analysis,IR, NMR and MS. Biological screening indicated that 5 compounds were effective against black rot of apple (Physalospora piricola Nose).

Key words: Imldazolinone, Cyclization, Triphosgene

TrendMD:

Wang Li-kun, Li Zheng-ming, Liu Tong-zhu, Jiang Yi-min . The Research on Development of Novel Pesticides (Ⅲ)--The Synthesis of Imidazolinones[J]. Chem. J. Chinese Universities, 1991, 12(7): 912.

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The Research on Development of Novel Pesticides (Ⅲ)--The Synthesis of Imidazolinones

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