Chem. J. Chinese Universities ›› 1990, Vol. 11 ›› Issue (8): 889.

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Reduction of Nitriles with Combined Reducing Agent——Sodium Borohydride/Iron Salts

Lin Ronghui, Zhang Yongmin, Zhou Zhiniu   

  1. Department of Chemistry, Hangzhou University, Hangzhou
  • Received:1988-12-29 Online:1990-08-24 Published:1990-08-24

Abstract: Under mild conditions both aromatic and aliphatic nitriles were reduced to corresponding primary amines by combined reducing agent——sodium borohydride/ferric chloride in moderate yields. The effect of various solvents and metal salts on the reduction were studied. The reaction mechanism was also discussed.

Key words: Reduction, Nitrile, Combined reducing agent

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