高等学校化学学报 ›› 1995, Vol. 16 ›› Issue (9): 1464.

• 研究简报 • 上一篇    下一篇

多肽净电荷数及等电点的计算

许旭1, 罗国安2, 林炳承3   

  1. 1. 中国药科大学药物分析教研室, 南京, 210009;
    2. 清华大学化学系;
    3. 中国科学院大连化学物理研究所
  • 收稿日期:1994-09-16 修回日期:1995-05-29 出版日期:1995-09-24 发布日期:1995-09-24
  • 通讯作者: 林炳承
  • 作者简介:许旭,男,30岁,博士研究生.
  • 基金资助:

    国家自然科学基金

Calculation on Isoelectric Point and Net Charge of Peptide

XU Xu1, LUO Guo-An2, LIN Bing-Cheng3   

  1. 1. Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, 210009;
    2. Department of Chemistry, Tsing-hua University;
    3. Dalian Institute of Chemical Physics
  • Received:1994-09-16 Revised:1995-05-29 Online:1995-09-24 Published:1995-09-24

关键词: 毛细管区带电泳, 多肽, 净电荷数, 等电点

Abstract: This paper shows a improved method using successive search method and adjusted dissociation constant for calculating isoelectric point and net charge at a certain pH of peptide,the result calculated is closed to the real value and is useful to study migration of peptide in Capillary Zone Electrophoresis (CZE).

Key words: Capillary zone electrophorisis, Peptide, Net charge, Isoelectric point

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