高等学校化学学报

高等学校化学学报 ›› 1995, Vol. 16 ›› Issue (12): 1874.

• 论文 • 上一篇    下一篇

α-(1,2,4-三唑-1-基)-α-苯甲酰基烯酮N,S;N,N;N,O和O,S-缩醛的合成及生物活性研究

李正名, 黄震年   

  1. 南开大学元素有机化学研究所, 天津, 300071
  • 收稿日期:1994-12-24 修回日期:1995-07-29 出版日期:1995-12-24 发布日期:1995-12-24
  • 通讯作者: 李正名,男,64岁,教授.
  • 作者简介:李正名,男,64岁,教授.
  • 基金资助:

    国家自然科学基金

Synthesis and Biological Activities of α-(1,2, 4-triazol-1-yl)-α-benzoylketene N,S;N,N;N,O and O,S-acetals

LI Zheng-Ming, HUANG Zhen-Nian   

  1. Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071
  • Received:1994-12-24 Revised:1995-07-29 Online:1995-12-24 Published:1995-12-24

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摘要： 以α-(1,2,4-三唑-1-基)-α-苯甲酰基烯酮二甲硫缩醛为反应中间体,与取代苯胺、邻苯二胺、乙二胺、乙醇胺和巯基乙醇反应,合成了27个标题化合物。初步的生物活性测定结果表明:所合成的部分化合物具有抑菌及植物生长调节活性。

关键词: 苯甲酰基烯酮缩醛, 1H-1, 2, 4-三唑, 生物活性

Abstract: Triazolylbenzoylketene S,S-acetals reacted with substituted phenylamines to give triazolylbenzoylketene N,S-acetals,and reacted with O-phenylenediamines,ethylenediamine, ethanolamines and 1-ethanol-2-thiol to afford the corresponding cyclic N,S;N,N;N,O and O,S-acetals. Their structures were identified by elementary and spectral analyses.The preliminary results of bioassay show that some of triazolylbenzoylketene N,S-acetals have plant-regulatory and fungicidal activities.

Key words: α-(1,2,4-Triazol-1-yl)-α-benzoylketene acetals, 1H-1,2,4-triazole, Bioassay

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