高等学校化学学报

高等学校化学学报 ›› 2001, Vol. 22 ›› Issue (S1): 141.

• 研究论文 • 上一篇    下一篇

1,5-二芳基二酮衍生物的制备-无溶剂状态下苯乙酮与芳基烯酮的共轭加成反应研究

刘万毅1, 李金夫1, 马永祥2, 梁永民2   

  1. 1. 宁夏大学化学科学与工程系, 银川 750021;
    2. 兰州大学化学化工学院, 兰州 730001
  • 收稿日期:2000-08-05 出版日期:2001-12-31 发布日期:2001-12-31
  • 通讯作者: 刘万毅(1963年出生),男,博士,教授,主要研究方向为有机合成化学应用化学.
  • 基金资助:

    宁夏大学博士启动基金资助.

Studies on NaOH-Catalyzed Conjugate Addition of Acetophenone with Chalcones under Solvent-Free Condition:Preparation of 1,5-Diketones

LIU Wan-Yi1, LI Jin-Fu1, MA Yong-Xiang2, LIANG Yong-Min2   

  1. 1. Department chemistry of Ninxia University, Yinchuan 750021, China;
    2. College of chemistry and Engineering of Lanzhou University, Lanzhou 730001, China
  • Received:2000-08-05 Online:2001-12-31 Published:2001-12-31

PDF (PC)

被引次数

3

摘要：

使苯乙酮作为亲核体,在无溶剂条件下,利用碱催化与烯酮发生共轭反应,合成了一系列新的1,5-二芳基二酮化合物.反应温和而方便、快速,收率在71~90%.

关键词: 无溶剂条件, 苯乙酮, 芳基烯酮, 1, 5-二芳基二酮

Abstract:

The paper has reported that commerical NaOH efficently catalyzes Michael reactions of chalcones (1) with acetophenone (2) under solvent-free conditions. And a series of 1,5-di aryldiketones can be obtained in 71-90% yields. All the product structures were characterized satisfactorily by IR.1HNMR.MS spectroscopy and elemental analysis. The procedure is performed by grinding the components with an agate mortar and a pestile under solvent-free at room temperature or preheating at 45℃ less than 1.3 hours. The result indicated that the aromatic systems are more active than the ferrocenyl analogous.

Key words: Under solvent-free, Acetophenone, Chalcones, 1,5-Diaryldiketones

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