高等学校化学学报

高等学校化学学报 ›› 2012, Vol. 33 ›› Issue (11): 2457.doi: 10.7503/cjcu20120335

• 有机化学 • 上一篇    下一篇

月季花抗氧化活性成分研究

王蕾, 符玲, 敬林林, 阿有梅, 贾陆   

  1. 郑州大学药学院, 郑州 450001
  • 收稿日期:2012-04-10 出版日期:2012-11-10 发布日期:2012-10-15
  • 通讯作者: 贾陆,男,博士,教授,主要从事天然药物化学研究.E-mail:jalujj@163.com E-mail:jalujj@163.com

Studies of Chemical Constituents from Rosa chinensis Jacq.

WANG Lei, FU Ling, JING Lin-Lin, A You-Mei, JIA Lu   

  1. School of Pharmacy, Zhengzhou University, Zhengzhou 450001, China
  • Received:2012-04-10 Online:2012-11-10 Published:2012-10-15

PDF (PC)

被引次数

9

摘要：

以活性追踪为指导分离和纯化了月季花中具有1,1-二苯基-2-三硝基苯肼(DPPH)自由基清除活性的成分. 从月季花中分离得到了10个黄酮类化合物, 采用光谱法对其结构进行了表征, 并对它们的自由基清除活性进行了评价. 结果表明, 化合物1为新化合物, 化合物1, 2, 4和9具有较强的清除DPPH自由基的活性.

关键词: 月季, 化学成分, 槲皮素3-O-(2",6"-二没食子酰基)-β-D-葡萄糖苷

Abstract:

In order to separate and purify the chemical constituents from Rosa chinensis Jacq., which have DPPH· scavenging capacity, dried Rosa chinensis flowers were extracted three times with 95% ethanol under reflux. This extract was then fractionated by column chromatography over silica gel, MCI gel, Sephadex LH-20, etc. A new compound[quercetin 3-O-(2",6"-digalloyl)-β-D-glucoside, 1] and nine known compounds (2-10) were isolated from Rosa chinensis Jacq. and identified using spectroscopic methods. Their antioxidant activity was assayed using DPPH· experiments. The results indicated that compounds 1, 2, 4 and 9 had good antioxidant activity.

Key words: Rosa chinensis Jacq., Chemical constituent, Quercetin 3-O-(2″,6″-digalloyl)-β-D-glucoside

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