高等学校化学学报 ›› 2011, Vol. 32 ›› Issue (1): 175.

• 研究论文 • 上一篇    下一篇

一种新的富勒烯封端聚L-谷氨酸苄酯的合成

张青环,傅凌云,张钧,杨新林   

  1. 北京理工大学生命科学学院, 北京 100081
  • 收稿日期:2010-03-15 修回日期:2010-07-15 出版日期:2011-01-10 发布日期:2010-12-11
  • 通讯作者: 杨新林 E-mail:xlyang@bit.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:   20672012)和北京市自然科学基金(批准号:  2082020)资助.

Synthesis of a Novel Fullerene End-capped Poly(γ-benzyl L-glutamate)

ZHANG Qing-Huan, FU Ling-Yun, ZHANG Jun, YANG Xin-Lin*   

  1. School of Life Science, Beijing Institute of Technology, Beijing 100081, China
  • Received:2010-03-15 Revised:2010-07-15 Online:2011-01-10 Published:2010-12-11
  • Contact: YANG Xin-Lin E-mail:xlyang@bit.edu.cn
  • Supported by:

    国家自然科学基金(批准号:   20672012)和北京市自然科学基金(批准号:  2082020)资助.

摘要: 首次利用富勒烯谷氨酸苄酯的游离氨基引发谷氨酸苄酯-NCA开环聚合,得到了一种新的富勒烯封端的聚谷氨酸苄酯.利用核磁共振(1HNMR)、红外光谱、紫外可见光谱、基质辅助激光解吸电离飞行时间质谱(MALDI-TOF-MS)和热重分析等对产物进行了表征.

关键词: 富勒烯封端聚谷氨酸苄酯, 开环聚合, 富勒烯衍生物引发剂

Abstract: Fullerene polymers have attracted much attention during the past decade. To explore the synthesis of fullerene polypeptides, a fullerene— γ—benzyl L—glutamate conjugate containing a free amino group was used as an initiator, polymerization of γ—benzyl L—glutamate N—carboxy— anhydride was performed for the first time via ring—opening polymerization, leading to formation of a novel fullerene end—capped poly(γ—benzyl L—glutamate) with a yield of 37.2%. The product was characterized by 1H NMR, FTIR, UV—VIS, MALDI—TOF MS and thermogravimetric analysis. Compared with previously reported method, this route avoids utilization of azides and affords the products with relatively identical structures, highlighting its potential application in fullerene polypeptide synthesis.

Key words: Fullerene end-capped poly(γ-benzyl L-glutamate), Ring-opening polymerization, Fullerene derivative initiator

TrendMD: