高等学校化学学报 ›› 2004, Vol. 25 ›› Issue (11): 2057-2059.

• 研究简报 • 上一篇    下一篇

两头尖的化学成分研究(Ⅱ)

夏忠庭1, 刘大有1, 王晓颖1, 杨秀伟2, 刘科峰1   

  1. 1. 长春中医学院药学院, 长春130021;
    2. 北京大学医学部, 北京100083
  • 收稿日期:2003-06-30 出版日期:2004-11-24 发布日期:2004-11-24
  • 基金资助:

    国家科技部“1035”工程(批准号:96-901-01-89);吉林省科技厅项目(批准号:20020503-14)资助

Chemical Constituents of Anemone raddeana Regel(Ⅱ)

XIA Zhong-Ting1, LIU Da-You1, WANG Xiao-Ying1, YANG Xiu-Wei2, LIU Ke-Feng1   

  1. 1. School of Pharmacy, Changchun College of Traditional Chinese Medicine, Changchun 130021, China;
    2. Department of Medicine, Peking University, Beijing 100083, China
  • Received:2003-06-30 Online:2004-11-24 Published:2004-11-24

关键词: 两头尖, 化学成分, 多被银莲花皂苷18

Abstract: Chinese folk medicine “Liang Tou Jian”(Anemone raddeana Regel) is the important medicine used to treat rheumatism, neuralgia, cancer and so on. Its chemical constituents were studied by chromatographing on silica gel and HPLC. A new triterpenoid saponin, raddeanoside 18, along with two known triterpenoid saponins, Hederacholichiside F and Leontoside D, was isolated from the ethanolic extrant of the rhizoma of Anemone raddeana Regel. Their structures were elucidated as 3-O-β-D-glucopyranosyl(1→4)[β-D-glucopyranosyl(1→2)]-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside(1), 3-O-β-D-glucopyranosyl(1→4)[α-L-rhamnopyranosyl(1→2)-]-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside(2), 3-O-β-D-glucopyranosyl(1→4)-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside(3) by 1D and 2D NMR ESI-MS and IR spectrometries, respectively.

Key words: Anemone raddeana, Chemical constituent, Raddeanoside 18

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