高等学校化学学报 ›› 2002, Vol. 23 ›› Issue (4): 600.

• 研究论文 • 上一篇    下一篇

蒺藜草中一个新的六糖甾体皂甙结构的NMR研究

涂光忠1, 马立斌1, 李喜来1, 安东各1, 孙文基2, 郭遵武2, 郜尽2   

  1. 1. 北京微量化学研究所, 北京 100091;
    2. 西北大学生物系, 西安 710061
  • 收稿日期:2000-12-15 出版日期:2002-04-24 发布日期:2002-04-24
  • 通讯作者: 涂光忠(1965年生),男,博士,副研究员,从事天然产物、多肽和蛋白质的结构研究.E-mail:tgz@microchem.org.cn E-mail:tgz@microchem.org.cn

Structure Elucidation of a New Saponin from Tribulus Terrestris L. Using High-field Gradient NMR Techniques

TU Guang-Zhong1, MA Li-Bin1, LI Xi-Lai1, AN Dong-Ge1, SUN Wen-Ji2, GUO Zun-Wu2, GAO Jin2   

  1. 1. Beijing Institute of Microchemistry, Beijing 100091, China;
    2. Department of Biology, Northwest Universiry, Xi'an 710069, China
  • Received:2000-12-15 Online:2002-04-24 Published:2002-04-24

摘要: 从蒺藜草中分离得到一个新的六糖甾体皂甙,利用NMR方法,特别是2DNMR技术,确定了它的化学结构为3-O-{β-D-吡喃木糖基-(1→3)-[β-D-吡喃葡萄糖基-(1→2)]-β-D-吡喃葡萄糖基-(1→4)-[α-L-吡喃鼠李糖基-(1→2)-β-D-吡喃半乳糖基}-22-甲氧基-26-O-{β-D-吡喃葡萄糖基}-蒺藜基皂甙元。

关键词: 蒺藜新甙, 1D TOCSY, 1D GOESY, 灵敏度增强HSQC, HSQC-TOCSY

Abstract: A new saponin was isolated from Thoulus terrestris L..By means of a series of 2DgradientNMRtechniques, including 1D gradient selective TOCSYand GEOSY, 2D gradient-COSY, NOESY,TOCSY, HSQC, HSQC-TOCSY, the structure of the saponin was elucidated as 26-O-β-D-glucopyra-nosyl-22-methoxy-furostane-3-O-{β-D-xyloPyranosyl-(1→3)-[β-D-xylopyranosyl-(1→2)-β-D-glucopy-ranosyl-(1→4)}-[α-L-rhamnopyranosyl-(1→2)]-β-D-galactopyranoside.

Key words: Terrestroneoside, 1D TOCSY, 1D GOESY, Sensitivity enhanced HSQC, HSQC-TOCSY

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