高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (7): 1056.

• 综合评述 • 上一篇    下一篇

环肽合成方法的研究进展

唐艳春, 田桂玲, 叶蕴华   

  1. 生物有机与分子工程教育部重点实验室, 北京大学化学与分子工程学院, 北京 100871
  • 收稿日期:1999-10-07 出版日期:2000-07-24 发布日期:2000-07-24
  • 通讯作者: 叶蕴华(1936年出生),女,教授,从事生物有机化学研究.
  • 基金资助:

    国家自然科学基金(批准号:29772001)资助

Progress in the Study on Synthetic Method of Cyclopeptide

TANG Yan-Chun, TIAN Gui-Ling, YE Yun-Hua   

  1. Key Laboratory of Bioorganic and Molecular Engineering of Education Ministry, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
  • Received:1999-10-07 Online:2000-07-24 Published:2000-07-24

PDF (PC)

被引次数

43

摘要： 介绍了纯环肽与杂环肽合成的方法、策略及其优缺点,列举了一些常用缩合试剂,探讨了反应溶液浓度、线型肽前体化合物的结构及构象等因素对环化反应的影响.

关键词: 环肽, 缩合试剂, 环化

Abstract: The synthetic method and strategy of cyclopeptide were presented, some efficient coupling reagents were introduced, and different influence factors such as the concentration of reaction solution, structure of linear peptide precursor, conformation etc, were discussed.

Key words: Cyclopeptide, Coupling reagent, Cyclization

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