高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (1): 5.

• 论文 • 上一篇    下一篇

稀土生物效应研究(Ⅰ)──正常人血浆中稀土含量及其物种分布

孟路, 丁兰, 陈杭亭, 赵大庆, 倪嘉缵   

  1. 中国科学院长春应用化学研究所, 长春 130022
  • 收稿日期:1998-01-14 出版日期:1999-01-24 发布日期:1999-01-24
  • 基金资助:

    国家自然科学基金

Biological Effectof Rare Earth(Ⅰ)-Content and Distribution of Rare Earth in Normal Human Plasma

MENG Lu, DING Lan, CHEN Hang-Ting, ZHAO Da-Qing, NI Jia-Zuan   

  1. Labortory of Rare Earth Chemistry and Physics, National A nalytical Research Center of Electro Chemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022
  • Received:1998-01-14 Online:1999-01-24 Published:1999-01-24

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摘要： 采用ICPMS及FPLC等技术研究了正常人血浆中稀土含量及其物种分布.结果表明,正常人血浆中含有痕量的稀土(总量为1.4133μg/L),每种稀土含量与其天然丰度一致;稀土物种主要集中于大分子蛋白组分中,与免疫球蛋白G(IgG)、运铁蛋白(Tf)、血清白蛋白(Alb)等均有作用,其中Tf结合稀土量较多.

关键词: 稀土, 血浆, 分布, ICP-MS, FPLC

Abstract: The content and distribution of rare Earth(RE)in normal human plasma have been in-vestigated by ult rafilt ration, FPL Cand ICP-MS methods.The results showed that there are trace RE in normal human plasma, and Their contents are in accordance with Their abundance.The RE can bond with immunoglobulin G(IgG), transferrin(Tf)and albumin(Alb)species, but mostly bond with if.

Key words: Rare earth, Plasma, Distribution, ICP-MS, FPLC

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