高等学校化学学报

高等学校化学学报 ›› 1995, Vol. 16 ›› Issue (2): 206.

• 研究简报 • 上一篇    下一篇

三螺旋DNA d(CT)8·d(AG)8·d(C+T)8的FT-Raman光谱

方晔1, 王霆1, 白春礼1, 魏莹1, 唐有祺1, 甘鲁生2   

  1. 1. 中国科学院化学研究所, 北京 100080;
    2. 台湾化学研究所
  • 收稿日期:1994-01-31 修回日期:1994-10-05 出版日期:1995-02-24 发布日期:1995-02-24
  • 通讯作者: 方晔,男,26岁,博士研究生.
  • 作者简介:方晔,男,26岁,博士研究生.
  • 基金资助:

    中国科学院“八五”重大项目

FT-Raman Spectroscopy of Triplex DNA d(CT)8·d(AG)8·d(C+T)8

FANG Ye1, WANG Ting1, BAI Chun-Li1, WEI Ying1, TANG You-Qi1, KAN Lou-Sing2   

  1. 1. Institute of Chemistry, Academia Sincia, Beijing, 100080;
    2. Institute of Chemistry, Academia Sinica, Taibei
  • Received:1994-01-31 Revised:1994-10-05 Online:1995-02-24 Published:1995-02-24

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关键词: 三螺旋DNA, FT-Raman光谱, 构象

Abstract: The conformation of triplex DNAd(CT)8·d(AG)8·d(C+T)8in solution has been investigated by near infrared FT-Raman spectroscopy at 1064 nm. Results clearly revealed that almost all of the sugar pukers of the triplex fall in the normal range for the Bgenus.However,a strong band at 1266 cm-1suggested that the C3'-endo/anti protonated cytosines in the third strand can not be eliminated.

Key words: Triplex DNA, FT-Raman spectra, Conformation

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