高等学校化学学报

高等学校化学学报 ›› 1989, Vol. 10 ›› Issue (5): 543.

• 研究简报 • 上一篇    下一篇

4-氟-3-羟基-1-取代苯基-6-哒嗪酮类结构及其反应的研究

袁斌, 林成极, 田官荣   

  1. 延边大学化学系
  • 收稿日期:1987-08-20 出版日期:1989-05-24 发布日期:1989-05-24
  • 通讯作者: 林成极

Studies on the Structures and Reactions of 4-Fluoro-3-hydroxyl-1 -substituted Phenyl-6-pyridazinones

Yuan Bin, Lin Chengji, Tian Guanrong   

  1. Department of Chemistry, Yanbian University, Yanji
  • Received:1987-08-20 Online:1989-05-24 Published:1989-05-24

PDF (PC)

被引次数

5

摘要： 氟代马来酐和苯肼缩合,反应先在乙醚后在25％盐酸中进行。4-氟-3-羟基-1-苯基-6-哒嗪酮(Ⅰ)的收率达54％,文献仅26％。Ⅰ和吗啡啉反应,得熔点为243～244℃的白色晶体。熔点及元素分析结果(表1)表明,产物为4-吗啡啉基-3-羟基-1-苯基-6-哒嗪酮(Ⅱ)[2],据此作者认为氟原子位于第4位。

关键词: 氟代哒嗪酮, 重氮甲烷, 甲基化

Abstract: The structures of 4-fluoro-3-hydroxy-l-phenyl and substituted phenyl-6-pyridazinones and their reactions with ethereal solution of diazome-thane were investigated. The methylation of this kind of pyridazinones indicates that the yield of O-CH3 derivatives is higher than that of N-CH3. Compound Ⅳ and Ⅵ exhibit a strong herbicidal effect, on barnyard grass, alisma orientalis etc. in rice-fields.

Key words: Fluoropyridazinone, Diazomethane, Methylation

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