高等学校化学学报 ›› 2017, Vol. 38 ›› Issue (7): 1155-1162.doi: 10.7503/cjcu20160783

• 分析化学 • 上一篇    下一篇

量子点荧光印迹传感器的计算机模拟设计、 制备及检测河水中4-硝基苯酚的应用

徐婉珍1, 邱春孝2, 黄卫红1, 刘鸿3, 杨文明2()   

  1. 1. 江苏大学环境与安全工程学院, 2. 材料科学与工程学院, 镇江 212013
    3. 吉林大学理论化学研究所, 理论化学计算实验室, 长春 130021
  • 收稿日期:2016-11-14 出版日期:2017-07-10 发布日期:2017-06-02
  • 作者简介:联系人简介: 杨文明, 男, 博士, 讲师, 主要从事分子印迹材料的计算机模拟、 合成及应用研究. E-mail: ywm@ujs.edu.cn
  • 基金资助:
    国家自然科学基金(批准号: 21677064)、 江苏省自然科学基金(批准号: BK20151323, BK20151337)和中国博士后科学基金(批准号: 2015T80515, 2014M560405)资助

Computer Simulation Design, Preparation and Application of Fluorescence Sensors Based on Quantum Dots for Selective Detection of 4-Nitrophenol in River Water

XU Wanzhen1, QIU Chunxiao2, HUANG Weihong1, LIU Hong3, YANG Wenming2,*()   

  1. 1. School of the Environment and Safety Engineering,2. School of Materials Science and Engineering, Jiangsu University, Zhenjiang 212013, China
    3. Institute of Theoretical Chemistry, Laboratory of Theoretical and Computational Chemistry,Jilin University, Changchun 130021, China
  • Received:2016-11-14 Online:2017-07-10 Published:2017-06-02
  • Contact: YANG Wenming E-mail:ywm@ujs.edu.cn
  • Supported by:
    † Supported by the National Natural Science Foundation of China(No.21677064), the Natural Science Foundation of Jiangsu Province, China(Nos BK20151323, BK20151337) and the Postdoctoral Science Foundation of China(Nos.2015T80515, 2014M560405)

摘要:

将量子点的荧光特性、 表面分子印迹技术与计算机模拟技术相结合, 分别以碲化镉、 4-硝基苯酚、 3-氨丙基三乙氧基硅烷和正硅酸四乙酯作为量子点、 模板分子、 功能单体和交联剂, 制得具有荧光特性的分子印迹聚合物. 对其结构、 形貌、 荧光性能和选择性进行了表征, 结果表明, 该聚合物对4-硝基苯酚具有良好的选择性和灵敏度, 线性范围为1.0~80 nmol/mL, 检出限为0.05 nmol/mL. 将制备的量子点荧光印迹聚合物作为传感器, 应用于河水中4-硝基苯酚的测定, 加标回收率为98.6%~101.2%, 相对标准偏差最高为1.37%.

关键词: 4-硝基苯酚, 荧光探针, 分子印迹, 量子点, 计算机模拟

Abstract:

To fabricate a fluorescent sensor,molecularly imprinted polymers(MIPs) with 4-nitrophenol(4-NP) as the template molecule were prepared on the surface of as-synthesized hybrid SiO2-coated CdTe(HS-QD) by combining molecular dynamics simulations with surface imprinting technique. The sensor was characterized by several methods in terms of structure, morphology, fluorescence properties and selectivity. The sensor has a higher sensitivity as well as good selectivity. The relative fluorescence intensity of HS-QD@MIP decreased linearly with the increasing concentration of 4-NP in the range of 1.0—80 nmol/mL with a detection limit of 0.05 nmol/mL. The method was also employed to detect 4-NP in the river water samples with satisfactory recoveries of 98.6%—101.2%, and the relative standard deviation was 1.37%.

Key words: 4-Nitrophenol, Fluorescence probe, Molecular imprinting, Quantum dot, Computer simulation

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