高等学校化学学报

高等学校化学学报 ›› 2012, Vol. 33 ›› Issue (10): 2289.doi: 10.7503/cjcu20120036

• 物理化学 • 上一篇    下一篇

316L钢表面纳米银镀层的制备、性质及血液相容性

薛歆1, 范立双2, 牛利2, 刘斌1, 常静1, 张晶1, 张基昌1, 赵雷1, 赵卓1, 李淑梅1   

  1. 1. 吉林大学白求恩第二医院, 长春 130041;
    2. 中国科学院长春应用化学所, 长春 130022
  • 收稿日期:2012-01-09 出版日期:2012-10-10 发布日期:2012-09-12
  • 通讯作者: 李淑梅, 女, 教授, 博士生导师, 主要从事心血管病研究. E-mail: xuexin_1982@sohu.com E-mail:xuexin_1982@sohu.com

Preparation, Property and Blood Compatibility of Nanometer Silver Plating on 316L Steel Surface

XUE Xin1, FAN Li-Shuang2, NIU Li2, LIU Bin1, CHANG Jing1, ZHANG Jing1, ZHANG Ji-Chang1, ZHAO Lei1, ZHAO Zhuo1, LI Shu-Mei1   

  1. 1. The Second Hospital of Jilin University, Changchun 130041, China;
    2. Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, China
  • Received:2012-01-09 Online:2012-10-10 Published:2012-09-12
  • Contact: Li Shumei E-mail:xuexin_1982@sohu.com

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被引次数

4

摘要：

采用恒电位电沉积方法在316L不锈钢表面沉积银纳米镀层, 并将钢板置于全氟硅烷溶液中浸泡, 通过动态凝血实验、 抗凝血时间测定、 血小板黏附实验、 溶血实验和蛋白吸附实验等手段, 测试材料的血液相容性. 结果表明, 通过上述方法可明显改善316L不锈钢的血液相容性, 而抗凝血性能、 溶血率及纤维蛋白吸附量不亚于裸钢板. 与316L裸不锈钢相比, 银镀膜全氟硅烷浸泡316L不锈钢具有良好的血液相容性, 是一种比较理想的冠状动脉支架材料, 具有良好的应用前景.

关键词: 恒电位电沉积, 316L不锈钢, 纳米银镀层, 疏水, 疏油, 血液相容性

Abstract:

Ag nanoparticles films were prepared by electrodeposition. The thin films were then treated with a avantin solution of 1H, 1H, 2H, 2H-perfluorooctyl triethoxysilane (25%, volume fraction) for 20 h. After these solution, 316L stainless steel’s surface mircoscopic view changed, so the hydrophobicity and oleophobic property were improved. The blood compatibility effect of the films was tested by dynamic blood coagulation experiment, anticoagulant time measurement, platelet adhesion experiment, hemolysis test, Protein adsorption experiment. As a result, platelet adsorption amount, activity level, albumin absorption amount have improved a lot by the nanometer silver plating on 316L steel surface, other index is similar with the bare steel. Nanometer silver plating on 316L steel surface can improve the blood compatibility of 316L steel. Compared with bare 316L stainless steel, Ag nanoparticles films has a better blood compatibility, it’s a appropriate material for coronary artery stent.

Key words: Facile electrochemical, 316L stainless steel, Ag nanoparticles film, Hydrophobicity, Oleophobic property, Blood compatibility

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