高等学校化学学报

高等学校化学学报 ›› 2012, Vol. 33 ›› Issue (06): 1350.doi: 10.3969/j.issn.0251-0790.2012.06.038

• 高分子化学 • 上一篇    下一篇

疏水性聚丙烯酸酯人工晶状体的低温等离子体改性

郑志雯, 邓凯敏, 任力, 王迎军   

  1. 国家人体组织功能重建工程技术研究中心, 华南理工大学材料科学与工程学院, 广州 510640
  • 收稿日期:2011-07-25 出版日期:2012-06-10 发布日期:2012-06-10
  • 通讯作者: 任 力, 男, 博士, 教授, 主要从事高分子生物材料研究. E-mail: psliren@scut.edu.cn E-mail:psliren@scut.edu.cn
  • 基金资助:

    国家"十一五"科技支撑计划(批准号: 2006BAI16B06)、国家自然科学基金(50732003, 50803018)、广东省科技计划项目(批准号: 2010B090400416)和中央高校基本科研业务费(批准号: 2011ZM0015)资助.

Surface Modification of Hydrophobic Acrylic Intraocular Lens by Ammonia Low-temperature Plasma

ZHENG Zhi-Wen, DENG Kai-Min, REN Li, WANG Ying-Jun   

  1. National Engineering Research Center for Human Tissue Restoration and Reconstruction, School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China
  • Received:2011-07-25 Online:2012-06-10 Published:2012-06-10

PDF (PC)

被引次数

6

摘要： 通过低温等离子体表面改性技术对疏水性聚丙烯酸酯人工晶状体进行表面改性, 并对改性前后材料的表面结构、形貌和光学性能进行了表征. 静态水接触角结果显示, 经过氨等离子体处理后的人工晶状体亲水性效果最好, 同时最佳的改性时间为120 s, 改性功率为150 W. XPS分析结果进一步证实, 经等离子体处理后, 在人工晶状体表面引入了极性基团. 原子显微镜观察结果显示, 改性后材料表面更加凹凸不平, 粗糙度显著增加而透光率变化很小, 但过大功率改性的样品透光率明显下降. 时效性测试结果表明, 人工晶状体在改性14 d后疏水性恢复趋于稳定.

关键词: 丙烯酸酯人工晶状体, 等离子体, 表面改性, 亲水性

Abstract: Hydrophobic acrylic intraocular lens is a novel soft material, which is different from the traditional polymethyl methacrylate(PMMA) lens. Surface modification of the lens surface with ammonia low-temperature plasma treatment was performed and characterized in order to enhance the hydrophilicity and biocompatibility. The results show that NH3 plasma treatment produce the most hydrophilic surface among O2, Ar and NH3 gases. The optimal modification time and power were 120 s and 150 W, respectively. XPS analyses further verified that the polar groups were immobilized on the lens surfaces. The AFM images of the treated samples show rougher surfaces with a significant increase in root mean square roughness(RMS). Transmittance exhibited small changes after modification in general. However, a larger power led to a sharp drop in the transmittance. According to the aging effect test, hydrophobic recovery occurred following the modification and tended to be stable after 14 d.

Key words: Acrylic intraocular lens, Plasma, Surface modification, Hydrophilicity

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