Synthesis and Crystal Structure of Diastereomeric Racemates 2-Amino-3-cyano-1-phenyl-4-(3,4-methylenedioxy phenyl)-2-cyclopenten-1-ol

Abstract

Abstract: The diastereomeric racemates ( 1S, 4R; 1R, 4S ) and ( 1S, 4S; 1R, 4R )2-amino-3-cyano-1-phenyl-4 (3,4-methylenedioxyphenyl)-2-cyclopentene-1-ols were synthesized by the catalysis of low-valent titanium reagent(TiCl₄-Zn) with 3-oxo-1-(3',4'-methylenedioxyphenyl)-3-phenylpropyl-1-propanedinitrile. Their relative configurations were determined by X-ray analysis.

Key words: Low-valent titanium reagent, Diastereomeric racemates, 2-Cyclopentene-1-ol, Crystal structure, Relative configuration

CLC Number:

O625

TrendMD:

SHI Da-Qing, LU Zai-Sheng, DAI Gui-Yuan . Synthesis and Crystal Structure of Diastereomeric Racemates 2-Amino-3-cyano-1-phenyl-4-(3,4-methylenedioxy phenyl)-2-cyclopenten-1-ol[J]. Chem. J. Chinese Universities, 1998, 19(9): 1426.

References

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