Chem. J. Chinese Universities ›› 1997, Vol. 18 ›› Issue (8): 1335.

• Articles • Previous Articles     Next Articles

A Facile Total Synthesis of 6-Pentyl-α-pyrone

ZHANG Chi, ZHANG Fang-Ning, WANG Xue-Chao, PAN Xin-Fu   

  1. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000
  • Received:1996-07-11 Online:1997-08-24 Published:1997-08-24

Abstract: 6-Pentyl-α-pyrone (6PP), a natural product with a number of bioactivies, has been synthesized from furfural in a five steps route. The key step is the epoxidation of 2-furyl-pentylcarbinol (3) with NBSin a mixed solvent system THFand H2O(4: 1). The overall yield is 34%.

Key words: 6-Pentyl-α-pyrone, Total synthesis, Epoxidation

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