Preparation and Characterization on Cecropin B Peptide Grafted with Silk Fibroin Films

Chem. J. Chinese Universities

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Preparation and Characterization on Cecropin B Peptide Grafted with Silk Fibroin Films

BAI Li-Qiang¹, MA Ting-Fang², YAO Ju-Ming¹*

1. The Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textile, Zhejiang Sci-Tech University, Hangzhou 310018, China;
2. Wensli Group Co. Ltd., Hangzhou 310021, China

Received:2007-01-22 Revised:1900-01-01 Online:2007-08-10 Published:2007-08-10
Contact: YAO Ju-Ming

Abstract

Abstract: The undisolvable Bombyx mori silk fibroin film was prepared from the regenerated silk fibroin solution followed with the 60%(volume fraction) ethanol aqueous solution treatment. The silk fibroin film was grafted with Cecropin B peptide via the carbodiimide chemistry. The secondary structure, the film surface properties and the bacteriostatic activity of the obtained silk fibroin film were analyzed with FTIR, SEM, EDS and the antibacterial tests. The results show that the Cecropin B peptide is covalently grafted onto the surface of silk fibroin film, which is undisolvable and has an effective and permanent bacteriostatic activity.

Key words: Silk fibroin film, Antibacterial peptide, Surface modification, Antibacterial material

CLC Number:

O636

TrendMD:

BAI Li-Qiang¹, MA Ting-Fang², YAO Ju-Ming¹*. Preparation and Characterization on Cecropin B Peptide Grafted with Silk Fibroin Films[J]. Chem. J. Chinese Universities, doi: .

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Preparation and Characterization on Cecropin B Peptide Grafted with Silk Fibroin Films

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