Fabrication of Novel Microdisk Sensor and Its Application to Monitoring Nitric Oxide Release from Single Cell

Chem. J. Chinese Universities

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Fabrication of Novel Microdisk Sensor and Its Application to Monitoring Nitric Oxide Release from Single Cell

DU Fu-Ying, HUANG Wei-Hua*, WU Wen-Zhan, WANG Zong-Li, CHENG Jie-Ke*

College of Chemistry & Molecular Science, Wuhan University, Wuhan 430072, China

Received:2007-03-22 Revised:1900-01-01 Online:2007-06-10 Published:2007-06-10
Contact: CHENG Jie-Ke

Abstract

Abstract: A novel nitrogen oxide(NO) sensor fabricated by modifying the only planar surface of a carbon fiber microdisk electrode(CFMDE) with single-walled carbon nanotubes(SWNTs) and Nafion membrane was reported for the first time. The modification of SWNTs dramatically improves the sensitivity of CFMDEs and the detection limit of NO was 4.3 nmol/L. The sensor was successfully applied to the measurement of NO released from single isolated human umbilical vein endothelial cells.

Key words: Nitric oxide, Ultramicrodisk electrode, Carbon nanotubes, Single cell release

CLC Number:

O657

TrendMD:

DU Fu-Ying, HUANG Wei-Hua*, WU Wen-Zhan, WANG Zong-Li, CHENG Jie-Ke*. Fabrication of Novel Microdisk Sensor and Its Application to Monitoring Nitric Oxide Release from Single Cell[J]. Chem. J. Chinese Universities, doi: .

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Fabrication of Novel Microdisk Sensor and Its Application to Monitoring Nitric Oxide Release from Single Cell

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