CJCU

Chem. J. Chinese Universities ›› 2010, Vol. 31 ›› Issue (8): 1488.

• Articles • Previous Articles     Next Articles

In-situ Synthesis and Properties of Hydroxyapatite-SOD Nanocomposite

WU Li-Yan1,2, WANG Yue-Yi1, YANG Dong-Sheng2, MENG Qing-Fan1, TENG Li-Rong1, GAO Bo1*   

  1. 1. College of Life Sciences, Jilin University, Changchun 130012, China;
    2. Department of Chemistry and Pharmacy, Zhuhai College, Jilin University, Zhuhai 519041, China
  • Received:2010-04-08 Online:2010-08-10 Published:2010-08-10
  • Contact: GAO Bo. E-mail: gaobo@jlu.edu.cn
  • Supported by:

    吉林省科技发展计划项目(批准号: 20070312)资助.

PDF (PC)

Abstract: Hydroxyapatite(HAP)-superoxide dismutase(SOD) nanocomposites(HAP-SOD) were in-situ synthesized using calcium acetate and ammonium dihydrogen phosphate as initial materials and characterized through X-ray diffraction(XRD), Fourier transform infrared spectroscopy(FTIR) and scanning electronic microscopy(SEM). Besides, SOD activity was detected and the release behavior was inspected. The results show that the particle size of HAP-SOD nanocomposite was under 100 nm, and the relative activity of SOD in the composites was up to 84.7%. The cumulative release rate of the complex was up to 81.2% in 24 h.

Key words: HAP-SOD nanocomposite, In-situ synthesis, Protein activity, Sustained-release

TrendMD: