Synthesis, Characterization, DNA-binding and Solvatochromic Properties of a New Ruthenium Complex

Abstract

Abstract: A new ruthenium complex of -(ClO₄)₂, where bpy=2,2'-bipyridine, dpapz=dipyrido₆-aza-phenazine was synthesized, and characterized by microanalyses, IR and ¹H NMR Spectra. The electronic absorption and emission spectral titration with DNA, DNA competitive binding with ethidium bromide, and viscosity measurements were carried out to study the calf thymus DNA binding properties of -(ClO₄)₂. The solvatochromism of the complex was also studied. The results indicate that the Ru(Ⅱ) complex acts as a DNA intercalator with a binding constant of 6.9×10⁵ L/mol at 50 mmol/L NaCl, and an emission sensor for solvent molecules.

Key words: Ruthenium complex, DNA binding, Solvatochromism

CLC Number:

O641.3

TrendMD:

WU Bao-Yan, GAO Li-Hua, WANG Ke-Zhi. Synthesis, Characterization, DNA-binding and Solvatochromic Properties of a New Ruthenium Complex[J]. Chem. J. Chinese Universities, 2005, 26(7): 1206.

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Synthesis, Characterization, DNA-binding and Solvatochromic Properties of a New Ruthenium Complex

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