Inhibition of Influenza Virus Infections in MDCK Cells by Rare Earth Borotungstates Heteropoly Blues with Mixed Valence

Abstract

Abstract: Transition} metal-substituted mixed-valence rare earth borotungsto-heteropoly blues, Ln₂H₃[BW₉^ⅥW₂^ⅤCo(H₂O)O₃₉]·nH₂O(Ln=La, Ce, Pr, Nd, Sm, Eu, Gd), were prepared and characterized by IR, UV, CV, TG-DTA, XPS and electrochemistry. The cell toxicity and antiviral activity of these rare earth borotungstate heteropoly blues were investigated on the inhibitory effect against influenza(A/H1N1/Jingfang/1/91, A/H₃N₂/Jingfang/30/95, B/Hufang/1/87) in MDCK cells, and the results suggest that these complexes exhibit an significantly inhibitory activity, which are comparable with those obtained from virazole, against influenza virus infection, and no cytotoxicity is shown on normal cells. The correlation(relation) between the structure of these complexes and their anti-virus activities was also discussed.

Key words: Rare earth borotungstoheteropoly blues, Rare earth, Influenza virus, Antiviral activity

CLC Number:

O614

TrendMD:

LIU Jie, MEI Wen-Jie, LI An-Xing, TAN Cai-Ping, SHI Shuo, JI Liang-Nian . Inhibition of Influenza Virus Infections in MDCK Cells by Rare Earth Borotungstates Heteropoly Blues with Mixed Valence[J]. Chem. J. Chinese Universities, 2004, 25(1): 1.

References

Related Articles 15

[1]	LU Cong, LI Zhenhua, LIU Jinlu, HUA Jia, LI Guanghua, SHI Zhan, FENG Shouhua. Synthesis， Structure and Fluorescence Detection Properties of a New Lanthanide Metal-Organic Framework Material [J]. Chem. J. Chinese Universities, 2022, 43(6): 20220037.
[2]	ZHOU Yonghui, LI Yao, WU Yuxuan, TIAN Jing, XU Longquan, FEI Xu. Synthesis of A Novel Photoluminescence Self-healing Hydrogel [J]. Chem. J. Chinese Universities, 2022, 43(2): 20210606.
[3]	WEI Chuangyu, CHEN Yanli, JIANG Jianzhuang. Fabrication of Electrochemical Sensor for Dopamine and Uric Acid Based on a Novel Dimeric Phthalocyanine-involved Quintuple-decker Modified Indium Tin Oxide Electrode [J]. Chem. J. Chinese Universities, 2022, 43(1): 20210582.
[4]	HAN Zongsu, YU Xiaoyong, MIN Hui, SHI Wei, CHENG Peng. A Rare Earth Metal-Organic Framework with H₆TTAB Ligand [J]. Chem. J. Chinese Universities, 2022, 43(1): 20210342.
[5]	LIANG Longqi, CHEN Cailing, YU Ying, LI Yuxin, LI Chunguang, SHI Zhan. Synthesis, Luminescence and Cell Imaging Properties of Amino Acid Capped YVO₄∶Eu Nanoparticles ^† [J]. Chem. J. Chinese Universities, 2020, 41(3): 425.
[6]	RAN Shiya,SHEN Haifeng,LI Xiaonan,WANG Zilu,GUO Zhenghong,FANG Zhengping. Effect and Mechanism of Rare Earth Trifluoromethanesulfonate on the Thermal Stability of Polypropylene^† [J]. Chem. J. Chinese Universities, 2019, 40(6): 1333.
[7]	LI Bing,WANG Xuemin,BAI Fengying,LIU Shuqing. Synthesises, Structures and Antibacterial Activities of a Series of Rare Earth Nitrogen Heterocyclic Complexes^† [J]. Chem. J. Chinese Universities, 2019, 40(4): 632.
[8]	LIANG Donglei, SONG Qiusheng, YAO Yutian, LIU Ben. Preparation of Complex Nanogel with Up-conversion Fluorescence-responsive Performance and Its Fluorescence Energy Transfer Behavior^† [J]. Chem. J. Chinese Universities, 2019, 40(3): 583.
[9]	ZHANG Yan, ZHANG Shengming, FANG Guizhen. Antioxidant Property of Catalyzed Lignosulfonate Using S₂ $O 8 2 -$ /ZrO₂ Doped Cerium as Catalysts^† [J]. Chem. J. Chinese Universities, 2018, 39(6): 1255.
[10]	TANG Keyun,LI Luoyuan,FU Limin,AI Xicheng,ZHANG Jianping. Effect of Crystal Matrix on Energy Transfer Mechanism in Rare-earth Upconversion Nanomaterials^† [J]. Chem. J. Chinese Universities, 2018, 39(10): 2136.
[11]	CHEN Chen, LI Li, CHEN Jinhua, ZHANG Xiaohua, XU Jie, LI Yibo, WEI Jie. Preparation and Electrocatalytic Performance for Methanol Oxidation of Pt-CeO₂/Sodium-4-styrenesulfonate Functionalized Carbon Nanotube Composites^† [J]. Chem. J. Chinese Universities, 2018, 39(1): 157.
[12]	GUO Zhenghong, FANG Zhengping, CHEN Chao. Synergistic Flame Retardant and Suppression Smoke Mechanism of Cerium Phenylphosphonate and Decabromodiphenyl Oxide in Glass-fiber Reinforced Poly(1,4-butylene terephthalate) Composites^† [J]. Chem. J. Chinese Universities, 2017, 38(2): 284.
[13]	WANG Xiaoqing, LING Jun, SHEN Zhiquan. Synthesis and Self-assembly of Thermoplastic Elastomer Poly(ε-decalactone)-Poly(L-lactide)-PEG with Rare Earth Catalyst^† [J]. Chem. J. Chinese Universities, 2016, 37(6): 1182.
[14]	LIU Rong, ZHA Fei, YANG Aimei, CHANG Yue. Synthesis of Light Olefins from CO₂ Hydrogenation Catalyzed over Rare Earths Modified CuO-ZnO-ZrO₂/SAPO-34^† [J]. Chem. J. Chinese Universities, 2016, 37(5): 964.
[15]	YANG Meiling, QIN Dongdong, SONG Yumin. Syntheses and Anticoagulant Action of Rare Earth Ternary omplexes with Warfarin and Ferulic Acid^† [J]. Chem. J. Chinese Universities, 2015, 36(5): 821.