Chemical Reaction of PHBV/Sol-gel Bioglass Foams for Born Tissue Engineering in Simulated Body Fluid

Abstract

Abstract: A new kind of porous composites prepared from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) and sol gel bioactive glass(SGBG) are used for born tissue engineering scaffolds. In this work, the chemical reaction and in vitro degradation of PHBV/SGBG porous materials was assessed in simulated body fluid(SBF). The changes in components and structures of the porous materials were investigated before and after immersion in SBF. It was found that the ion concentrations of SBF changed with immersing time because of ion exchange reaction and degradation reaction of PHBV/ SGBG in SBF solution. FTIR and XRD analysis indicated that hydroxyl carbonate apatite(HCA) had formed on the surface of PHBV/SGBG after the porous scaffold was exposed to SBF solution for 12 h.

Key words: Degradation, Simulated body fluid, Poly(3-hydroxybutyrate-co-3-hydroxyvalerate), Sol-gel bioactive glass

CLC Number:

O631

TrendMD:

ZHENG Yu-Dong, WANG Ying-Jun, CHEN Xiao-Feng, REN Yao-Bin, WU Gang . Chemical Reaction of PHBV/Sol-gel Bioglass Foams for Born Tissue Engineering in Simulated Body Fluid[J]. Chem. J. Chinese Universities, 2003, 24(7): 1325.

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Chemical Reaction of PHBV/Sol-gel Bioglass Foams for Born Tissue Engineering in Simulated Body Fluid

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