Preparation and Evaluation of Octadecyl-Zirconia Bonded Stationary Phases

Abstract

Abstract: Porous zirconia particles, synthesized by polymerization-induced colloid aggregation (PICA)method, were modified with octadecyltrimethoxysilane compounds for reversed-phase high-performanceliquid chromatography.These stationary phases were evaluated in terms of reversed-phase chro-matographic properties with different volume ratos of methanol to water.Stability studies conducted at anextreme pH (pH = 2.0 and pH = 12.0) have shown that octadecyl-zirconia sorbents are no more stablethan ODSunder acidic conditions, but rather stable under basic conditions.The retention of non-polar andslightly polar compounds was quasi-homoenergetic on octadecyl-zirconia stationary phases.

Key words: Zirconia, HPLC, Octadecyl-zirconia bonded stationary phase (ODZ)

CLC Number:

O658

TrendMD:

YANG Jun-Jiao, WANG Hui, ZUO Yu-Min . Preparation and Evaluation of Octadecyl-Zirconia Bonded Stationary Phases[J]. Chem. J. Chinese Universities, 2002, 23(5): 835.

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Preparation and Evaluation of Octadecyl-Zirconia Bonded Stationary Phases

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