Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (S1): 63.

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Study on the Anticancer Activity of Indigo Derivatives

MENG Ji-Ben, LI Ping, HE Yong-Zhi, XU Li-Li, WANG Yong-Mei   

  1. Department of Chemistry, Nankai University, Tianjin 300071, China
  • Received:2001-06-25 Online:2001-12-31 Published:2001-12-31
  • Contact: mengjiben@eyou.com E-mail:mengjiben@eyou.com

Abstract:

Thirteen compounds of indigo derivatives were synthesized, among which six compounds were first synthesized, The structure of all the new compounds have been comfirmed by 1H NMR, MS and elemental analysis. The relationship between the compound's structure and anticancer activity was studied. It was found that most of the indigo derivatives have the similar anticancer activity to indirubin, and some superior than indirubin.

Key words: Indigo, Indirubin, Anticancer activity

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