Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (9): 1515.

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A New Diterpene Lactone from the Soft Coral Sarcophyton molle Tix. Dur.

SU Jing-Yu, YAN Su-Jun, ZENG Long-Mei   

  1. Department of Chemistry, Zhongshan University, Guangzhou 510275, China
  • Received:2000-07-08 Online:2001-09-24 Published:2001-09-24

Abstract: Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. Its structure was determined to be C-1 epimer of sarcophinone by spectroscopic methods. Bioassay showed that both sarcophinone(1) and iso sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.

Key words: Soft coral, Diterpenoids, Structural detemination, Cytotoxicity

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