Evaluation of the Cytotoxicity About Photic Organic Nanoparticles

doi:10.3969/j.issn.0251-0790.2012.01.036

Abstract

Abstract: The cytotoxicity about organic nanoparticles which has the function of two-photon fluorescent probe 2,5,2',5'-tetra(4'-N,N-diphenylaminostyryl)biphenyl(DPA-TSB) was studied. The physiological activity of stomach cancer cells after englobing the nanoparticle was detected by the methods of WAT-1, Lactate dehydrogenase(LDH) and flow cytometry. The results show that the stomach cancer cells can live well when the concentration of the nanoparticles is below 12 μg/mL, which suggests that the nanoparticles have the property of good biological security.

Key words: Organic nanoparticles, Cytotoxicity, Flow cytometry

CLC Number:

O631
R114

TrendMD:

LI Xiao-Dong, YANG Shu-Min, XU Hong, MA Yu-Guang. Evaluation of the Cytotoxicity About Photic Organic Nanoparticles[J]. Chem. J. Chinese Universities, 2012, 33(01): 210.

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