Synthesis and QSAR of Herbicidal 3-Alkoxy-6-(substituted)phenoxypyridazines

Abstract

Abstract: Aseries of3-alkoxyl-6-(substituted)phenoxypyridazines were synthesized in good yields by a novel synthetic approach, the nucleophilic reaction of3,6-bis (substituted)phenoxypyridazines with alkoxides.Their pI₅₀value against barnyard grass and greenhouse activity against barnyard grass, common crabgrass, rape, amaranth were tested.The results showed that some of them exhibited a higher activity than MH.The primary quantitative sturcture activity relationship(QSAR) was discussed

Key words: Substituted)phenoxypyridazines, Herbicidal activity, Synthesis, QSAR

CLC Number:

O641.3

TrendMD:

REN Kang-Tai, SONG Hong-Hai, YANG Xiu-Feng, YANG Hua-Zheng . Synthesis and QSAR of Herbicidal 3-Alkoxy-6-(substituted)phenoxypyridazines[J]. Chem. J. Chinese Universities, 2000, 21(12): 1840.

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Synthesis and QSAR of Herbicidal 3-Alkoxy-6-(substituted)phenoxypyridazines

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