Studies on Synthesis and Funigicidal Activity of S-Allyl-O-substituted Phenyl Thiophosphates(onates)

Abstract

Abstract: The isomerization/chlorination of O,O-diallyl thiophosphates(onates) 6with phosphorus oxychloride gives Sallyl thiophosphorochloridate(nochloridate)7 and Oallyl phosphorodichloride 8. After removal of 8 under the reduced pressure, the crude 7 is purified by column chromatography on silica gel, then 7 reacts with substituted phenoLIn chloroform in the presence of triethylamine giving eighteen new title compounds 9. The bioassay results against five plant disease fungi including P. Zeae, P. Piricola, R. Solani, A. Solani and D. Arachidicala show that the title compounds 9 possess some or excellent fungicidal activity at 0.005% concentration.

Key words: Isomerization, Chlorination, Thiophosphoric(nic) ester, Fungicidal activity

CLC Number:

O621.25

TrendMD:

HE Zheng-Jie, LIU Ju-Xiang, ZHOU Zheng-Hong, TANG Chu-Chi . Studies on Synthesis and Funigicidal Activity of S-Allyl-O-substituted Phenyl Thiophosphates(onates)[J]. Chem. J. Chinese Universities, 1999, 20(2): 227.

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Studies on Synthesis and Funigicidal Activity of S-Allyl-O-substituted Phenyl Thiophosphates(onates)

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