Synthesis and Fungicidal Activity of 3-Anilinomethylene-5,6-dihydro-6-alkyl(aryl)-2H-pyran-2,4-diones

Abstract

Abstract: 3-Anilinomethylene-6-alkyl(aryl)-5,6-dihydro-2H-pyran-2,4-diones(3) were pre-pared by the condensation reaction of 6-alkyl(aryl)-5,6-dihydro-2H-pyran-2,4-diones(1), substituted anilines(2) and ethyl orthoformate. Apair of conformationaLIsomers 4 and 5 exist in products 3 due to the formation of the intramolecular hydrogen bond. Compound 3 was tested in vitro against many fungi such as P. Zeae, C. Arachidicala, P. Piricola, A. Solani, B. Cinerae, S. Sclerotiorum, H. Oryzae, etc . The bioassay results show that they have some fungicidal activity.

Key words: Condensation reaction, Intra molecular hydrogen bond, ConformationaLIsomers, Fungicidal activity

CLC Number:

O621.12

TrendMD:

WANG You-Ming, LI Zheng-Ming, LI Jia-Feng, LI Shu-Zheng, ZHANG Su-Hua . Synthesis and Fungicidal Activity of 3-Anilinomethylene-5,6-dihydro-6-alkyl(aryl)-2H-pyran-2,4-diones[J]. Chem. J. Chinese Universities, 1999, 20(10): 1559.

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Synthesis and Fungicidal Activity of 3-Anilinomethylene-5,6-dihydro-6-alkyl(aryl)-2H-pyran-2,4-diones

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