Chem. J. Chinese Universities ›› 1999, Vol. 20 ›› Issue (1): 81.

• Articles • Previous Articles     Next Articles

Synthetic Studies of HIV-active Didemnaketal A Analogue--Synthesis of a C8-C15 Fragment

TU Yong-Qiang, LIU Zeng-Lu, WANG Ping-Zhen, JIA Yan-Xing   

  1. Department of Chemistry, National Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000
  • Received:1998-04-15 Online:1999-01-24 Published:1999-01-24

Abstract: A C8-C15 fragmentof The HIV-active didemnaketal Aanalogue was synthesized from (+)R-pulegone through 5 steps.One new chiral center, The C12, was successf ully const ructed by The steric induction in this approach.These intermediates were characterized by 1HNMR.

Key words: Spiroketa, Intermediate, Chiral synThesis

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