Abstract: FT-IR spectroscopy was used to study the conformation transition of silk fibroin in poly (acrylonitrile-co-methyl acrylate)-poly-L-alanine (PANMA-PLAL) blends, PANMA-silk fibroin(SF) blends, and poly (acrylic acid sodium) (NA)-SF blends. It was found that, in these blends, intermolecular hydrogen bonds will form between the carbonyl group of other polymers and the amide of SF. To form these hydrogen bonds, SFmust change its conformation. The possible structure of the hydrogen bonds and the mechanism of the formation of the hydrogen bonds were also discussed.

Key words: Silk fibroin, FT-IR, Blends, Conformation transition