Chem. J. Chinese Universities ›› 1997, Vol. 18 ›› Issue (7): 1054.

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Synthetic Studies on-2-Substituted-1,7-dioxaspiro[4.4]nonan-8-one

WANG En-Si1, SHEN Jia-Cong2, Henry N. C. WONG3   

  1. 1. Department of Molecular Biology, Changchun 130023;
    2. Dept.of Chem.T, Jilin University, Changchun 130023;
    3. Department of Chemistry, The Chinese University of Hong Kong, Hong Kong
  • Received:1996-10-29 Online:1997-07-24 Published:1997-07-24

Abstract: Employing base-promote intromolecular Michael addition as a pivotal step, 3-(3-hydroxybutyl)-2-buten-4-olide (1, 3 and 5) have been converted to disubstitued-1, 7-dioxas-piro[4.4]nonan-8-one(2, 4 and 6) under different conditions.

Key words: Intromolecular Michael addition, 2-Substituted-1, 7-dioxaspiro[4,4] nonan-8-one, Synthesis

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