Chem. J. Chinese Universities ›› 1996, Vol. 17 ›› Issue (3): 392.

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Synthesis of Diacetylenic Lipids and Studies on the Preparation and Stability of Polymerized Liposomes

YU Kai1, SUN Yan1, ZHANG Bao-Shen2, ZNOU Xiu-Zhong2   

  1. 1. Department of Chemical Engineering, Tianjin University, Tianjin 300072;
    2. Department of Chemistry, Nankai University
  • Received:1995-02-11 Online:1996-03-24 Published:1996-03-24

Abstract: The seven lipids with diacetylenic structure were synthesized,using lipids Ⅰ-Ⅶ polymerized liposomes were prepared,and their stabilitics under different environmental conditions(e.g.,alcohol,acid,alkaline,salt and buffer solutions)were investigated.The results indicated that the polymerized liposome prepared with pentacosa-10, 12-diyne-1-olphosphoryl ethanolamine exhibited an enhanced stabilities.

Key words: Lipid, Polymerized liposome, Stability

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