Synthesis of Some Novel Sulfonylureas Containing Thiadiazole and Their Biological Activity

Chem. J. Chinese Universities ›› 1995, Vol. 16 ›› Issue (2): 234.

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Synthesis of Some Novel Sulfonylureas Containing Thiadiazole and Their Biological Activity

YANG Xin-Ling, CHEN Fu-Heng

Department of Applied Chemistry, Beijing Agricultural Univiversity, Beijing, 100094

Received:1994-02-21 Revised:1994-08-03 Online:1995-02-24 Published:1995-02-24

Abstract

Abstract: Twenty-five novel sulfonylureas containing thiadiazole have been synthesized by treating 2-amino-5-subthiadiazole with sulfonylisocynate.Tlieir structures were confirmed by IR,¹HNMR and elementary analysis.The preliminary biological test shows that compounds 1,2,5 and 22 are effective against broadleaf plants at 2.25 kg/ha in pre-or post-emergence;10,22,25 also exhibit certain fungicidal activity against puccinia Recondita at 0.125%in vivo.

Key words: Thiadiazole, Sulfonylurea, Synthesis, Biological activity

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YANG Xin-Ling, CHEN Fu-Heng. Synthesis of Some Novel Sulfonylureas Containing Thiadiazole and Their Biological Activity[J]. Chem. J. Chinese Universities, 1995, 16(2): 234.

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Synthesis of Some Novel Sulfonylureas Containing Thiadiazole and Their Biological Activity

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