Chem. J. Chinese Universities ›› 1992, Vol. 13 ›› Issue (4): 487.

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The Stereospecific Synthesis of 3-Methyl-5-Phenylsulfonyl-3E-Penten-1-ol

MAO Jian-min1, LI Wei-dong1, LI Ying1, LI Yu-lin1, LIANG Xiao-tian2   

  1. 1. Institute of Organic Chemistry, the State Key Laboratory oj Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000;
    2. Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, 100050
  • Received:1991-04-23 Online:1992-04-24 Published:1992-04-24

Abstract: The stereospecific synthesis of 3-methyl-5-phenylsulfonyl-3E-penten-1-ol (1) was accomplished by using 4-hydroxyl-2-butone(2) as the starting material through four steps.The key step in synthesis is the stereospecific rearrangement of allylic alcohol(4).

Key words: 3-Methyl-5-phenylsulfonyl-3E-penten-l-ol, Synthesis, Stereospecificity

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