Sythnesis and Effect of p-(Diethylamino)phenylgermanium Sesquioxide on Human Breastcarcinoma Cells in Vitro

Chem. J. Chinese Universities ›› 1992, Vol. 13 ›› Issue (12): 1510.

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Sythnesis and Effect of p-(Diethylamino)phenylgermanium Sesquioxide on Human Breastcarcinoma Cells in Vitro

LU Chuan-Xin¹, ZHANG Shu-Gong¹, NI Jia-Zuan¹, NIE Yu-Xiu²

1. Changchun Institute of Applied Chemistry, Academia Sinica, Changchun, 130022;
2. Norman Bethune University of Medical Science, Changchun

Received:1992-04-11 Revised:1992-06-09 Online:1992-12-24 Published:1992-12-24

Abstract

Abstract: The organogermanium compound p-(diethylamino)phenylgermanium sesquioxide was prepared with a simplified method,and the structure and properties were characterized.The results of the cancer cell culture show that in the concentration range of 1.00～0.01mmol/Lof the compound in the culture solution does not nearly inhibit the mitoses of human breastcarcinoma cells.

Key words: p-(Diethylamino)phenylgermanium sesquioxide, Organogermanium, Synthesis, Cell culture, Anticancer

TrendMD:

LU Chuan-Xin, ZHANG Shu-Gong, NI Jia-Zuan, NIE Yu-Xiu, CHEN Yu-Lan. Sythnesis and Effect of p-(Diethylamino)phenylgermanium Sesquioxide on Human Breastcarcinoma Cells in Vitro[J]. Chem. J. Chinese Universities, 1992, 13(12): 1510.

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Sythnesis and Effect of p-(Diethylamino)phenylgermanium Sesquioxide on Human Breastcarcinoma Cells in Vitro

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