24-Methylene-Cholestane-3β,5α,6β,19-tetraol--a Novel Polyhydroxylated Sterol with Rare 19-Hydroxyl Group

Abstract

Abstract: A novel polyhydroxylated sterol, Nephalsterol-A(1)with rare 19-hydroxyl group was obtained from the ethanol extracts of the soft corals Nephthea albida and Nephthea tiexieral verseveldt collected from Xisa Islands and Nansa Islands respectively, colorless needle crystal, m. p. 242-243℃, [α]_D²⁰ = 0(C 0. 053, MeOH). The structure of (1) has been established as 24-methylene-Cholestane-3β, 5α,6β,19-tetraol by means of IR, ¹HNMR, ¹³CNMR and MS technique.

Key words: Soft corals, (Nephthea albida,Nephthea tixiexae verseveldt), Sterol, 24-Methylene-cholestane-3β,5α,6β,19-tetraol

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Zeng Long-mei, Wang Guiyangsheng, Li Feng-ying, Zhong Yong-li . 24-Methylene-Cholestane-3β,5α,6β,19-tetraol--a Novel Polyhydroxylated Sterol with Rare 19-Hydroxyl Group[J]. Chem. J. Chinese Universities, 1991, 12(7): 910.

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24-Methylene-Cholestane-3β,5α,6β,19-tetraol--a Novel Polyhydroxylated Sterol with Rare 19-Hydroxyl Group

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