高等学校化学学报 ›› 1991, Vol. 12 ›› Issue (5): 633.

• 论文 • 上一篇    下一篇

光活性α-对氯苯基异戊酸和α-异丙基对氯苄胺作为拆分剂的应用研究

王敏, 胡秉方   

  1. 北京农业大学应用化学研究所, 100094
  • 收稿日期:1990-02-05 出版日期:1991-05-24 发布日期:1991-05-24
  • 通讯作者: 王敏
  • 基金资助:

    国家自然科学基金

Studies on the Application of Optically Active 2-(4-Chlorophenyl)-3-Methylbutanoic Acid and α-Isopropyl-4-Chlorobenzylamine as Resolving Agent

Wang Min, Hu Bing-fang   

  1. Institute of Applied Chemistry, Beijing Agricultural University, Beijing, 100094
  • Received:1990-02-05 Online:1991-05-24 Published:1991-05-24

摘要: 碱性拆分剂的选择不象酸性拆分剂的选择那么有限,但在众多合成的碱性拆分剂中,既廉价易得,而又有高拆分效果的物质很少。最常用的α-苯乙胺,由于其水溶性,有时会使拆分遇到困难。

关键词: 拆分, &alpha, -对氯苯基异戊酸, &alpha, -异丙基对氯苄胺

Abstract: Optically active 2-(4-chlorophenyl)-3-methylbutanoic acid and its degradation product, optically active α-isopropyl-4-chlorobenzylamine were efficiently used for the resolution of racemic bases such as PTE, PEA, erythro-DPAE, and recemic acids such as trans-chrysanthemic acid and as-partic acids.

Key words: Resolution, 2-(4-chlorophenyl)-3-methylbutanoic acid, α-iso-Propyl-4-chlorooenzy-lamine

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