高等学校化学学报 ›› 2001, Vol. 22 ›› Issue (9): 1515.

• 研究简报 • 上一篇    下一篇

柔软肉芝软珊瑚中的新二萜内酯

苏镜娱, 闫素君, 曾陇梅   

  1. 中山大学化学系, 广州 510275
  • 收稿日期:2000-07-08 出版日期:2001-09-24 发布日期:2001-09-24
  • 通讯作者: 曾陇梅(1930年出生),男,教授,博士生导师,主要从事天然有机化学研究.E-mail:ceszlm@zsu.edu.cn E-mail:ceszlm@zsu.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:29772058;2992030);“九五”国家科技专项“南沙群岛及其邻近海区综合科学考察”项目(批准号:97-926-02-03)资助

A New Diterpene Lactone from the Soft Coral Sarcophyton molle Tix. Dur.

SU Jing-Yu, YAN Su-Jun, ZENG Long-Mei   

  1. Department of Chemistry, Zhongshan University, Guangzhou 510275, China
  • Received:2000-07-08 Online:2001-09-24 Published:2001-09-24

关键词: 软珊瑚, 二萜内酯, 结构测定, 细胞毒性

Abstract: Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. Its structure was determined to be C-1 epimer of sarcophinone by spectroscopic methods. Bioassay showed that both sarcophinone(1) and iso sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.

Key words: Soft coral, Diterpenoids, Structural detemination, Cytotoxicity

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