高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (1): 84.

• 研究简报 • 上一篇    下一篇

寡糖快原子轰击质谱中碱金属加合离子应用技术的研究

赵凡智, 翟建军, 陈耀祖   

  1. 兰州大学应用有机化学国家重点实验室, 兰州 730000
  • 收稿日期:1997-12-13 出版日期:1999-01-24 发布日期:1999-01-24
  • 通讯作者: 赵凡智,男,52岁,高级工程师.

The Study of Alkali Metal Adductions Technique of Oligosaccharides in Fast Atom Bombardment Mass Spectrometry

ZHAO Fan-Zhi, ZHAI Jian-Jun, CHEN Yao-Zu   

  1. National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000
  • Received:1997-12-13 Online:1999-01-24 Published:1999-01-24

摘要: 生命科学的研究成果[1~3]表明,糖蛋白和糖脂中的糖基可作为细胞的识别信号,能控制细胞的分裂和分化.快原子轰击(FAB)质谱是测定寡糖的重要手段[4,5],但目前还存在不少问题.我们在对麦芽各糖的研究中.

关键词: 寡糖, FAB谱, 加合离子

Abstract: In positiveion fast atom bombardment(FAB)mass spectrometry, it is difficult to determine The molecular w eights of oligosaccharides due to the low abundance of[M+H]+ion How ever, when oligosaccharides are mixed with an appropriate amountof NaCl and LiCl, two highly abundant peaks[M+LI]+and[M+Na]+appear in FAB mass spectra and Their mass diff erence is 16.from The adductions, The molecular weights of oligosaccharides can be determineddef initively.this technique has not been reported previously.

Key words: Oligosaccharide, Fastatom bombardment spectra, Adduction

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