高等学校化学学报

高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (9): 1426.

• 论文 • 上一篇    下一篇

非对映消旋体2-氨基-3-氰基-1-苯基-4-(3,4-亚甲二氧苯基)-2-环戊烯-1-醇的合成和晶体结构

史达清, 路再生, 戴桂元   

  1. 徐州师范大学化学系, 徐州, 221009
  • 收稿日期:1997-08-06 出版日期:1998-09-24 发布日期:1998-09-24
  • 通讯作者: 史达清,男,35岁,副教授.
  • 作者简介:史达清,男,35岁,副教授.
  • 基金资助:

    江苏省青年科技基金资助课题.

Synthesis and Crystal Structure of Diastereomeric Racemates 2-Amino-3-cyano-1-phenyl-4-(3,4-methylenedioxy phenyl)-2-cyclopenten-1-ol

SHI Da-Qing, LU Zai-Sheng, DAI Gui-Yuan   

  1. Department of Chemistry, Xuzhou Normal University, Xuzhou, 221009
  • Received:1997-08-06 Online:1998-09-24 Published:1998-09-24

PDF (PC)

被引次数

2

摘要： 用低价钛试剂(Ticl4-Zn)与3-氧代-1-(3',4'-亚甲二氧苯基)-3-苯基丙基-1-丙二腈反应合成了非对映消旋体(1S,4R;1R,4S)和(1S,4S;1R,4R)2-氨基-3-氰基-1-苯基-4-(3,4-亚甲二氧苯基)-2-环戊烯-1-醇,用X射线衍射分析确定了这两个异构体的相对构型.

关键词: 低价钛试剂, 非对映消旋体, 2-环戊烯-1-醇, 晶体结构, 相对构型

Abstract: The diastereomeric racemates ( 1S, 4R; 1R, 4S ) and ( 1S, 4S; 1R, 4R )2-amino-3-cyano-1-phenyl-4 (3,4-methylenedioxyphenyl)-2-cyclopentene-1-ols were synthesized by the catalysis of low-valent titanium reagent(TiCl4-Zn) with 3-oxo-1-(3',4'-methylenedioxyphenyl)-3-phenylpropyl-1-propanedinitrile. Their relative configurations were determined by X-ray analysis.

Key words: Low-valent titanium reagent, Diastereomeric racemates, 2-Cyclopentene-1-ol, Crystal structure, Relative configuration

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