高等学校化学学报 ›› 1988, Vol. 9 ›› Issue (4): 333.

• 论文 • 上一篇    下一篇

单纯形优化高效液相色谱法分离测定维生素E的各种异构体

邓勃, 陈培榕, 蔡小嘉   

  1. 清华大学化学系
  • 收稿日期:1986-10-07 出版日期:1988-04-24 发布日期:1988-04-24
  • 通讯作者: 邓勃
  • 基金资助:

    中国科学院科学基金

Simplex Optimization of HPLC to Separate and Determine Vitamin E Isomers

Deng Bo, Chen Pejrong, Cai Xiaojia   

  1. Department of Chemistry, Tainghua University, Beijing
  • Received:1986-10-07 Online:1988-04-24 Published:1988-04-24

摘要: 本文用计算机辅助单纯形优化高效液相色谱法分离、测定了精炼植物油副产物中维生索E的各种异构体。探讨了单纯形优化法指导高效液相色谱选择分离的实验条件,并编写了实用的计算机程序。实验结果表明,本法可使比较困难的条件选择工作有章可循,从而提高工作效率。

关键词: 单纯形优化, 维生素E, 异构体, 植物油

Abstract: The paper describes HPLCmethod for the determination of α-, β-,γ-,δ-isomers of Vitamin Ein by-products of refined plant oil. Asimplex method wasadopted to optimize the chromatographic conditions and a practical program was worked out. The experimental results are acceptable and the simplex method is proved to be very useful for selection of conditions in HPLC.

Key words: Simplex optimization, Vitamin E, Isomer, Plantoil

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