高等学校化学学报 ›› 2016, Vol. 37 ›› Issue (10): 1769-1775.doi: 10.7503/cjcu20160298

• 研究论文: 无机化学 • 上一篇    下一篇

α-氨基酸各官能团对其Co(Ⅱ)配合物可逆氧合性能的影响

薛鹏1,2, 魏雅娜1,3, 岳凡1, 张翼2, 王吉德1()   

  1. 1. 新疆大学化学与化工学院, 石油天然气精细化工教育部和自治区共建重点实验室, 乌鲁木齐 830046
    2. 中南大学化学与化工学院, 生物传感与表面分析研究所, 长沙 410083
    3. 新疆应用职业技术学院石油与化学工程系, 奎屯 833200
  • 收稿日期:2016-04-29 出版日期:2016-10-10 发布日期:2016-09-20
  • 作者简介:联系人简介: 王吉德, 男, 博士, 教授, 主要从事配位化学和催化研究. E-mail:awangjd@sina.cn
  • 基金资助:
    国家自然科学基金(批准号: 21162027, 21261022)资助

Effects of Functional Groups in α-Amino Acids on Reversible Oxygenation Performance of Co(Ⅱ) Complexes

XUE Peng1,2, WEI Yana1,3, YUE Fan1, ZHANG Yi2, WANG Jide1,*()   

  1. 1. Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education & Xinjiang Uygur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China
    2. Institute of Biosensing and Surface Analysis, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
    3. Petroleum Chemical Engineering Department, Xinjiang Career Technical College, Kuitun 833200, China
  • Received:2016-04-29 Online:2016-10-10 Published:2016-09-20
  • Contact: WANG Jide E-mail:awangjd@sina.cn
  • Supported by:
    † Supported by the National Natural Science Foundation of China(Nos.21162027, 21261022)

摘要:

选择氧合性能良好的组氨酸(His)-Co(Ⅱ)作为研究对象, 分别掩蔽—NH2、 取代—O-和去除—COO-, 得到短肽、 伪肽和多胺等类组氨酸结构. 采用UV-Vis光谱法研究了α-氨基酸中的3个官能团对其Co(Ⅱ)配合物氧合性能的影响. 对比研究表明: α-氨基酸中—NH2对其Co(Ⅱ)配合物的吸氧性具有决定作用; —COO-对其Co(Ⅱ)配合物氧合作用的可逆性起关键作用; 而—O-对其Co(Ⅱ)配合物的吸氧性影响不大. 在前期研究结果的基础上, 对α-氨基酸-Co(Ⅱ)配合物可逆吸收和释放O2的机理进行了探讨.

关键词: α-氨基酸, Co(Ⅱ)配合物, 可逆氧合, 组氨酸, 氧载体

Abstract:

In this paper, we selected histidine-Co(Ⅱ) complex as the target for researching its good oxygenation performance, and obtained short peptide, pseudo peptide and histamine through masking —NH3+, replacing —O- and removing —COO-, respectively. The impacts of three functional groups in α-amino acids on the oxygenation performance of their Co(Ⅱ) complexes were investigated via UV-Vis spectrophotometry. The comparative study showed that in α-amino acids, the —NH3+ group plays a decisive role in oxygenation properties, —COO- group plays a key role in reversibility of oxygenation, and —O- has little influence on absorbing oxygen of complexes. The mechanism of α-amino acid-Co(Ⅱ) complexes reversible absorbing and releasing O2 are discussed on the basis of previous research results.

Key words: α-Amino acid, Co(Ⅱ) complex, Reversible oxygenation, Histidine, Oxygen carrier

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