关键词: 两性离子水凝胶, 溶胶-凝胶法, 紫外光引发, 有机/无机杂化溶胶, 抗菌黏附性能

Abstract:

To construct a zwitterionic polymer hydrogel layer on the surfaces of various substrates, a poly-merizable and crosslinkable organic/inorganic hybrid material or an organosilicon/SiO₂ hybrid sol was employed as a transition layer between the substrate and the zwitterionic monomer layer. The reactions involving double bonds in the zwitterionic monomer solution and the sol were initiated by UV irradiation to produce the zwitterionic polymer layer and the hybrid layer that plays an assistive bonding role, thus constructing the zwitterionic hydrogel layer on the substrate surface. The surfaces of the zwitterionic hydrogel layer and the hybrid layer were characterized by attenuated total reflectance Fourier transform infrared(ATR FTIR) spectroscopy, atomic force microscope(AFM) and contact angle measurement. Based on these analyses, the anti-bacterial adhesion performances of the glass surface modified with zwitterionic gel layer and the untreated glass surface as a control sample were investigated and analyzed by the bacterial adhesion experiment using S. aerues and E. coli as a test strain, respectively. The results indicate that it is effective to introduce the linear siloxane chains [(Si-(CH₂)₂-O-] to the organosilicon/SiO₂ hybrid transition layer for increasing its adhesion to the substrate surface and improving its flexibility. The zwitterionic hydrogel layer can be simply and firmly grafted onto the substrate surface through the UV-initiated reactions of double bonds in the zwitterionic monomer solution and the sol. Compared to the corresponding control sample, the glass surface modified with the zwitterionic hydrogel can exhibit an obvious antibacterial adhesion performance.

Key words: Zwitterionic hydrogel, Sol-gel method, UV photoinitiation, Organic/inorganic hybrid sol, Antibacterial adhesion performance