Chem. J. Chinese Universities ›› 2002, Vol. 23 ›› Issue (3): 419.

• Articles • Previous Articles     Next Articles

Studies on the Synthesis and Bioactivity of Pinacolone(or Arylethanone) Containing 1H-1,2,4-Triazole Group and Their Derivatives

XU Liang-Zhong, LU Xiao-Lan, ZHANG Shu-Sheng, JIAO Kui   

  1. Department of Applied Chemistry, Qingdao Institute of Chemical Technology, Qingdao 266042, China
  • Received:2000-12-18 Online:2002-03-24 Published:2002-03-24

Abstract: Sixteen new compounds containing 1H-1,2,4-triazole group were synthesized through C-alkylation of α-(1H-1,2,4-triazol-1-yl) pinacolone (or 1-arylethanone) with arylthioalkyl bromide and their structures were confirmed by 1H NMR spectra, IR, MS and elemental analysis. Preliminary biological test shows that the synthesized compounds exhibited some fungicidal activity.

Key words: 1H-1,2,4-Triazole, Fungicidal activity, Synthesis

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